Tc-Glutathione Complex (Tc -GSH) : Labelling, Chemical Characterization and Biodistribution in Rats
نویسندگان
چکیده
منابع مشابه
Tc-Glutathione Complex (Tc -GSH) : Labelling, Chemical Characterization and Biodistribution in Rats
The chemical structure of (99m)Tc-GSH has been estabilished using the (99)Tc isotope. Labeling of glutathione with technetium in the presence of stanous chloride gave a high yield result. In a comparative study between (99)Tc and (99)Tc glutathione, the Tc-GSH complex obtained was purified and characterized by uv, visible spectroscopy, HPLC, Biogel chromatography, mass and NMR spectroscopy. Sto...
متن کاملBiodistribution of Tc-99m Labeled Isoniazid Solid Lipid Nanoparticles in Wistar Rats
In this study Isoniazid (INH) as one of the first line drugs in treatment of Tuberculosis was investigated to be loaded in Solid Lipid Nanoparticles (SLNs) for reducing hepatotoxicity as well as prolonging drug release. High shear homogenization method was performed to prepare INH SLNs. To compare biodistribution of INH before and after loading in SLNs, INH was labeled by Technetium 99 (Tc99) a...
متن کاملBiodistribution of Tc-99m Labeled Isoniazid Solid Lipid Nanoparticles in Wistar Rats
In this study Isoniazid (INH) as one of the first line drugs in treatment of Tuberculosis was investigated to be loaded in Solid Lipid Nanoparticles (SLNs) for reducing hepatotoxicity as well as prolonging drug release. High shear homogenization method was performed to prepare INH SLNs. To compare biodistribution of INH before and after loading in SLNs, INH was labeled by Technetium 99 (Tc99) a...
متن کاملLyophilized Kits for Labelling with Tc
the purification and identification of reduced antibody fraction by spectrophotometer method; mass of Anti-CEA and MDP; time and temperature of lyophilized method. The best conditions for lyophilized kits were selected and the labelling efficiency was determined using ascending paper chromatography on Whatman 3MM paper and TLC-SG in 0.9 % saline and methyl ethyl ketone as a solvent. This work b...
متن کاملCharacterization theorems for PDL and FO(TC)
Our main contributions can be divided in three parts: (1) Fixpoint extensions of first-order logic: we give a precise syntactic and semantic characterization of the relationship between FO(TC) and FO(LFP). (2) Automata and expressiveness on trees: we introduce a new class of parity automata which, on trees, captures the expressive power of FO(TC) and WCL (weak chain logic). The latter logic is ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Metal-Based Drugs
سال: 1999
ISSN: 0793-0291
DOI: 10.1155/mbd.1999.329